以骨免疫、口腔再生医学为研究方向，基于免疫调节胶原膜促进软硬组织再生的相关研究成果发表于Nature Communications、Implant dentistry、International Journal of Oral and Maxillofacial Surgery、Materials Science & Engineering C等国际期刊上。先后获得2项国家自然科学基金及多项省部级项目资助。现任中华口腔医学会计算机专委会委员。作为副主编或参译，编写专著译著6部，作为副主编的专著入选人卫社中国医药学术原创精品图书出版工程。先后完成多项国家发明专利及1项实用新型专利转化。代表性论著：1. Yang Yang， Chenyu Chu， Li Liu， Chenbing Wang， Chen Hu， Shengan Rung， Yi Man*， Yili Qu*; Tracing immune cells around biomaterials with spatial anchors during large-scale wound regeneration， Nature Communications， 2023， Accepted in principle.2. Jiayu Gao， Xiangqi Zhao， Yi Man， Yili Qu*. Effect of the implant apical exposure and coverage < or ≥ 2 mm bone graft on transcrestal sinus floor elevation: a 1‑ to 7‑year retrospective cohort study. Clinical Oral Investigations. 2023， https://doi.org/10.1007/s00784-023-04974-8.3. Yang Yang， Chenyu Chu， Wenlan Xiao， Li Liu， Yi Man， Jie Lin， Yili Qu*. Strategies for advanced particulate bone substitutes regulating the osteo-immune microenvironment. Biomedical Materials. 2022， 17(2): 022006. DOI: 10.1088/1748-605X/ac5572.4. Chen Deng， Zumu Yi， Chenyi Xiong， Yi Man*， Yili Qu*. Using the intact periosteum for horizontal bone augmentation of peri-implant defects: A retrospective cohort study. British Journal of Oral and Maxillofacial Surgery. 2022.. DOI: 10.1016/j.bjoms.2022.09.012.5. Chenyu Chu， Li Liu， hengan Rung， Yuanjing Wang， Yuxing Ma， Chen Hu， Xiwen Zhao， Yi Man， Yili Qu*. Modulation of foreign body reaction and macrophage phenotypes concerning microenvironment. Journal of Biomedical Materials Research. 2020， 108A: 127-135.